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The genotoxic potential of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™) was evaluated i...

关键词: -methoxy-6-chloro-9-[3-(2-chloroethyl)aminopropylamino] acridine 2HCl    2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide    2-aminoanthracene    2AA    AF-2    Ames test    Animals    B[a]P    CHL    Cell Line    Cells, Cultured    Chinese hamster lung    Chromosome aberration test    Cricetulus    DMSO    Female    GSH    Genotoxicity    Humans    ICH    ICR-191    International Conference on Harmonization    Lung    Lymphocytes    MI    MMC    MMS    Mice    Mice, Inbred ICR    Micronucleus test    Mutagenicity Tests    N-methyl-D-aspartate    NGF    NMDA    NaN(3)    PQQ    PQQ Cofactor    Pyrroloquinoline quinone    Salmonella typhi    US    United States    benzo[a]pyrene    body weight    bw    dimethyl sulfoxide    glutathione    methyl methanesulfonate    mitomycin C    mitotic index    nerve growth factor    pyrroloquinoline quinone disodium salt    revolutions per minute    rpm    sodium azide   
期刊:Regul Toxicol Pharmacol  影响因子:0.0  发表日期: 20131101  PMID: 23891671 


Oxidative stress has been implicated in the pathology of the lethal skeletal muscle disease Duche...

关键词: -2-oxothiazolidine-4-carboxylate    2-[6-(4-aminophenoxy)-3-oxo-3H-xanthen-9-yl]benzoic acid    2-mercaptoethanol    2ME    4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid    5,5′-dithiobis-(2-nitrobenzoic acid)    ACN    APF    Acetylcysteine    Animals    BODIPY FL-N-(2-aminoethyl) maleimide    CK    CS    CTAB    DMD    DTNB    Disease Models, Animal    Duchenne muscular dystrophy    EGTA    FLM    GSH    GSSG    HEPES    MPO    Male    Mice    Mice, Inbred C57BL    Muscular Dystrophy, Duchenne    N-ethylmaleimide    NEM    OPA    OTCl    Oxidative Stress    Oxidative stress    PBS    Pyrrolidonecarboxylic Acid    ROS    SDS    SDS-PAGE    TCA    TCEP    TNF    Taurine    Texas Red C2-maleimide    Texas red    Thiazolidines    acetonitrile    citrate synthase    creatine kinase    ethylene glycol tetraacetic acid    glutathione    hexadecyltrimethylammonium bromide    l-2-Oxothiazolidine-4-carboxylate    mdx mice    myeloperoxidase, N-acetylcysteine    o-phthalaldehyde    oxidized glutathione    phosphate buffered saline    reactive oxygen species    sodium dodecyl sulphate    sodium dodecyl sulphate polyacrylamide gel electrophoresis    trichloroacetic acid    tris(2-carboxyethyl)phosphine    tumor necrosis factor   
期刊:Int J Biochem Cell Biol  影响因子:0.0  发表日期: 20130901  PMID: 23892094 


The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR), and thior...

关键词: AhpC    AhpF    Alkyl hydroperoxide peroxidase subunit C    Alkyl hydroperoxide peroxidase subunit F    Animals    Anti-Bacterial Agents    Antioxidants    B. subtilis    BSO    Bacillus subtilis    Bacterial Proteins    Bacterioferritin comigratory protein    Bcp    Buthionine sulfoximine    Catalase    Dihydrolipoamide succinyltransferase    E. coli    E. faecalis    Entercoccus faecalis    Escherichia coli    FAD    Flavin adenine dinucleotide    GPx    GR    GSH    GST    Glutaredoxin    Glutathione    Glutathione peroxidise    Glutathione reductase    Glutathione transferase    Grx    H. pylori    HDAC    HTLV-1    Helicobacter pylori    Histone deacetylases    Human T-lymphotropic virus type I    Humans    KatA    KatG    Keap1    Kelch-like ECH-associated protein 1    M. tuberculosis    MSH    Methionine-O-sulfoxide reductase    Methionine-S-sulfoxide reductase    Microbial Viability    Mrx    MsrA    MsrB    Mtr    Mycobacterium tuberculosis    Mycoredoxin    Mycothione    Mycothione reductase    NADPH    Nicotinamide adenine dinucleotide phosphate    Nrf2    Nuclear factor erythroid-related factor 2    Oxidative Stress    PDI    Peroxidases    Peroxiredoxin    Protein disulfide isomerase    Prx    RNR    ROS    Ribonucleotide reductase    S. aureus    S. pyogenes    Sec    Staphylococcus aureus    Streptococcus pyogenes    SucB    TGR    TS(2)    TXNIP    Thiol peroxidase    Thioredoxin    Thioredoxin glutathione reductase    Thioredoxin interacting protein    Thioredoxin reductase    Thioredoxin-Disulfide Reductase    Thioredoxins    Tpx    Trx    TrxR    TryR    Trypanothione    Trypanothione reductase    U, selenocysteine    WT    Wild type    antioxidant    catalase peroxidase    glutathione    peroxiredoxin    reactive oxygen species    thioredoxin   
期刊:Free Radic Biol Med  影响因子:0.0  发表日期: 20140101  PMID: 23899494 


Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liv...

期刊:Toxicol Ind Health  影响因子:1.378  发表日期: 20160101  PMID: 23907830 


OBJECTIVE: This study investigated the effects of dietary methionine restriction (MR) on the prog...

关键词: 3-Hydroxybutyric Acid    ALT    AST    Acac    Acadvl    Adiponectin    Animals    ApoB    Biomarkers    Blood Glucose    C-C chemokine receptor-2    CF    Ccr2    Cd 36    Chrebp    Cpt1a    Dgat    Diet    Disease Progression    EGF-like module-containing mucin-like hormone receptor-like 1    Emr1    FAO    FFA    Fasn    Fatty Acids    Fatty Liver    Fatty acid oxidation    Fatty liver    GSH    Gene Expression Regulation    Gpam    HDL    HFD    HMW    HOMA    Hadha and Hadhb    Homeostasis    IL6    IR    Inflammation    Insulin    Itgax    LDL    Leptin    Lipid Metabolism    Lipoproteins, VLDL    Liver    Lxr    MR    Male    Methionine    Mice    Mice, Obese    Mttp    NAFLD    NASH    Obesity    Oxidation-Reduction    Pklr    Pnpla2    Pnpla3    Pparα    Pparγ    ROS    Scd1    Severity of Illness Index    Srebf1    TG    TNF-α    Triglyceride    Triglycerides    VLDL    acetyl-CoA carboxylase    acyl-coenzyme A dehydrogenase, very long chain    alanine aminotransferase    apolipoprotein B    aspartate aminotransferase    carbohydrate regulatory binding protein    carnitine palmitoyltransferase-1a    control-fed    diacylglycerol O-acyltransferase    fatty acid oxidation    fatty acid synthase    free fatty acids    glutathione    hepatic CD36 antigen    high-density lipoprotein    high-fat diet    high-molecular-weight    homeostasis model assessment    hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A thiolase/enoyl-coenzyme A hydratase (trifunctional protein), alpha and beta subunits, respectively    insulin resistance    integrin alpha X    interleukin-6    liver X-receptor    low-density lipoprotein    methionine restriction    microsomal triglyceride transfer protein    mitochondrial glycerol-3-phosphate acyltransferase    non-alcoholic fatty liver disease    non-alcoholic steatohepatitis    ob/ob    obese mouse    patatin-like phospholipase domain containing 2    patatin-like phospholipase domain containing 3    peroxisome proliferator-activated receptor α    peroxisome proliferator-activated receptor γ    pyruvate kinase-liver and red blood cell    reactive oxygen species    stearoyl-coenzyme A desaturase-1    sterol regulatory element binding transcription factor 1    triglycerides    tumor necrosis factor-α    very-low-density lipoprotein   
期刊:Metab Clin Exp  影响因子:0.0  发表日期: 20131101  PMID: 23928105 


8-Nitroguanosine 3',5'-cyclic monophosphate (8-nitro-cGMP) is a unique derivative of guanosine 3'...

关键词: 15-deoxy-Δ(12,14)-prostaglandin J(2)    15d-PGJ(2)    1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one    2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide    4-hydroxy-2-nonenal    4H-8-bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one    60-kDa heat-shock protein    8-Nitro-cGMP    8-bromo-cGMP    8-bromoguanosine 3′,5′-cyclic monophosphate    8-nitroguanosine 3′,5′-cyclic monophosphate    ATP    Animals    CBS    CSE    Cyclic GMP    ELISA    ETC    Electrophile    GSH    GTP    HNE    HO-1    HPLC-ECD    HSP60    Humans    Hydrogen sulfide    IFN-γ    IL-1β    Keap1    Kelch-like ECH-associated protein 1    LC–MS/MS    LPS    MI    MPO    N(G)-nitro-l-arginine methyl ester    N(ω)-monomethyl-l-arginine    NADPH oxidase    NADPH oxidase 2    NOS    NS 2028    Nox    Nox2    Nrf2    ODQ    Oxidative stress    PDEs    PKG    PTM    Protein Processing, Post-Translational    Protein S-guanylation    RAR    RNOS    ROS    SOD    Signal Transduction    TNFα    adenosine 3′,5′-cyclic monophosphate    adenosine 5′-triphosphate    cAMP    cGMP    cGMP-dependent protein kinase    cPTIO    cystathionine β-synthase    cystathionine γ-lyase    eNOS    electron transport chain    endothelial NOS    enzyme-linked immunosorbent assay    glutathione    guanosine 3′,5′-cyclic monophosphate    guanosine 5′-triphosphate    heme oxygenase-1    high-performance liquid chromatography with electrochemical detector    iNOS    inducible NOS    interferon-γ    interleukin-1β    l-NAME    l-NMMA    lipopolysaccharide    liquid chromatography with tandem mass spectrometry    mPTP    mitochondrial permeability transition pore    myeloperoxidase    myocardial infarction    nNOS    neuronal NOS    nitric oxide synthases    nuclear factor erythroid 2-related factor 2    pGC    particulate-type guanylyl cyclase    phosphodiesterases    post-translational modification    reactive nitrogen oxide species    reactive oxygen species    retinoic acid receptor    sGC    soluble-type guanylyl cyclase    superoxide dismutase    tumor necrosis factor α   
期刊:Nitric Oxide  影响因子:0.0  发表日期: 20131101  PMID: 23632125 


Helical nanofibres of silver(I)-glutathione (Ag-GSH) biocoordination polymer (BCP) are fabricated...

期刊:Philos Trans A Math Phys Eng Sci  影响因子:0.0  发表日期: 20131013  PMID: 24000359 


The new complex [Rh2(phen)2(CH3CN)6](BF4)4 (1) was synthesized and characterized in solution and ...

期刊:Philos Trans A Math Phys Eng Sci  影响因子:0.0  发表日期: 20130728  PMID: 23776291 


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