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OBJECTIVES: To analyse the determinants of raltegravir CSF penetration, including the pharmacogen...

期刊:J Antimicrob Chemother  影响因子:0.0  发表日期: 20140101  PMID: 23975735 


Brain iron accumulation has been implicated in a host of chronic neurological diseases, including...

关键词: 6-OHDA    6-hydroxydopamine    AD    ALS    Alzheimer's disease    BBB    Brain    DFO    EGCG    EPO    F-box/leucine-rich repeat protein 5, GLUT, glucose transporter    FBXL5    Free Radicals    Free radicals    GSH    HIF    HO-1    Homeostasis    Humans    IRE    Iron    Iron Chelating Agents    Iron chelation    L-DOPA    MAO    MPTP    N-methyl-4-phenyl-1,2,3,6-tertahydropyridine    Neuroprotection    Neuroprotective Agents    OS    PD    PHD    Parkinson Disease    Parkinson's disease    ROS    Reactive Oxygen Species    SNpc    SOD    Substantia Nigra    TH    Tf    TfR    UPDRS    UPS    Unified Parkinson's Disease Rating Scale    VEGF    amyotrophic lateral sclerosis    blood–brain barrier    desferrioxamine    epigallocatechin 3-gallate    erythropoietin    glutathione    heme oxygenase-1    hypoxia-inducible factor    iron-responsive element    l-dihydroxyphenylalanine    monoamine oxidase    oxidative stress    prolyl-4-hydroxylase    reactive oxygen species    substantia nigra pars compacta    superoxide dismutase    transferrin    transferrin receptor    tyrosine hydroxylase    ubiquitin–proteasome system    vascular endothelial growth factor.   
期刊:Free Radic Biol Med  影响因子:0.0  发表日期: 20130901  PMID: 23376471 


The neuroactive steroids 17β-estradiol and progesterone control a broad spectrum of neural functi...

关键词: AD    AQP    ATP    Alzheimer's disease    Animals    Astrocytes    Astroglia    BBB    BSA    Brain Injuries    CNS    Ca(2+)/calmodulin-dependent protein kinases    CaMK    EAE    ER    ERK    Estrogen    G-protein coupled receptor 30    GFAP    GLAST    GLT-1    GPR30    Gonadal Steroid Hormones    Humans    ICI    ICI 182,780    IGF    IL    Ko    MAPK    MHC    MMP    MNAR    Microglia    NF-κB    Neuroprotective Agents    PELP1    PI3K    PKA    PKC    Progesterone    RCEs    ROS    SERM    Src    TGF-β    TNF-α    VEGF    adenosine triphosphate    aquaporin    blood–brain barrier    bovine serum albumin    central nervous system    estrogen receptor    experimental autoimmune encephalomyelitis    extracellular signal-related kinase    glial fibrillary acidic protein    glutamate transporter-1    gutamate–aspartate transporter    iNOS    inducible nitric oxide synthase    insulin-like growth factor-1    interleukin    knockout    major histocompatibility complex    matrix metalloproteinase    mitogen-activated protein kinase    modulator of nongenomic activity of ER    nuclear factor-kappa B    phosphatidylinositol 3-kinases    proline, glutamate and leucine rich protein1    protein kinase A    protein kinase C    radical oxygen species    respiratory chain enzymes    sarcoma    selective estrogen receptor modulator    siRNA    small interfering RNA    tMCAO    transforming growth factor-beta    transient middle cerebral artery occlusion    tumor necrosis factor-alpha    vascular endothelial growth factor   
期刊:J Steroid Biochem Mol Biol  影响因子:0.0  发表日期: 20130901  PMID: 23196064 


OBJECTIVE: IMM-H004 (7-hydroxy-5-methoxy-4-methyl-3-[4-methylpiperazin-1-yl]-2H-chromen-2-one) is...

期刊:J Stroke Cerebrovasc Dis  影响因子:0.0  发表日期: 20171001  PMID: 28669655 


AIM: Our goal was to develop an efficient nanoparticle-based system that can overcome the restric...

期刊:Nanomedicine (Lond)  影响因子:0.0  发表日期: 20170701  PMID: 28621578 


Tong-Qiao-Huo-Xue Decoction (TQHXD) is a classical prescription in traditional Chinese medicine t...

期刊:Chem Pharm Bull  影响因子:1.133  发表日期: 20170101  PMID: 29093286 


Systemic therapy is an important backbone in the multimodal treatment approach of brain metastase...

期刊:Handb Clin Neurol  影响因子:0.0  发表日期: 20180101  PMID: 29307361 


Brain cancer is a highly lethal disease, especially devastating toward both the elderly and child...

期刊:Nanomedicine (Lond)  影响因子:0.0  发表日期: 20180101  PMID: 29161215 


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