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BACKGROUND: Studies have reported gene-by-environment interaction for chronic respiratory conditi...

期刊:Mutat Res  影响因子:0.0  发表日期: 20130901  PMID: 23648357 


Chronic kidney disease (CKD) which can lead to end-stage renal failure remains a principal challe...

期刊:Nephrol Dial Transplant  影响因子:0.0  发表日期: 20140901  PMID: 23975750 


Parkinson disease (PD) is a complex neurodegenerative disorder with both motor and nonmotor sympt...

关键词: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine    1-methyl-4-phenylpyridinium    6-OHDA    6-hydroxy dopamine    Animals    DBS    Disease Models, Animal    Free radicals    GBA    GWAS    Genes    Genetic Predisposition to Disease    HLA    Humans    IL    Inflammation    LAMP2A    LPS    LRRK2    MAO-B    MPP(+)    MPTP    Mitochondria    Mitochondrial dysfunction    Mutation    NMS    Nerve Degeneration    Neuroprotection    Oxidative Stress    Oxidative stress    PD    PGC-1α    PINK1    Parkinson Disease    Parkinson disease    Protein handling    SNc    STN    Substantia Nigra    TNF-α    UCH-L1    UPS    alpha-Synuclein    deep brain stimulation    genome-wide association studies    glucocerebrosidase    human leukocyte antigen    interleukin    leucine-rich repeat kinase 2    lipopolysaccharide    lysosome-associated membrane protein type 2A    mitochondrial DNA    monoamine oxidase-B    mtDNA    nonmotor symptoms    peroxisome proliferator-activated receptor γ coactivator-1α    phosphatase and tensin homolog-inducible kinase 1    substantia nigra pars compacta    subthalamic nucleus    tumor necrosis factor-α    ubiquitin carboxyl-terminal hydrolase L1    ubiquitin–proteasome system   
期刊:Free Radic Biol Med  影响因子:0.0  发表日期: 20130901  PMID: 23380027 


The use of high-throughput omics may help to understand the contribution of genetic variants to t...

期刊:Rheum Dis Clin North Am  影响因子:0.0  发表日期: 20170801  PMID: 28711145 


This review highlights the basic paradigms and directions of molecular genetic studies of cogniti...

期刊:Zh Nevrol Psikhiatr Im S S Korsakova  影响因子:0.0  发表日期: 20160101  PMID: 28635752 


Obsessive-compulsive disorder (OCD) and Autism spectrum disorder (ASD) are both highly heritable ...

关键词: ASD    GWAS    Heritability    Meta-analysis    OCD    Polygenic score   
期刊:Eur Neuropsychopharmacol  影响因子:0.0  发表日期: 20170701  PMID: 28641744 


Osteoarthritis (OA) is a widespread disease characterized by a multifaceted etiopathogenesis and ...

关键词: GWAS    Osteoarthritis    SNP    epigenetics    epigenetyka    miRNA    osteoartroza   
期刊:Ortop Traumatol Rehabil  影响因子:0.0  发表日期: 20170510  PMID: 29086737 


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