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TMPRSS2/ERG is the most common type of gene fusions found in human prostate cancer. There are two...

关键词: ERG    FACS    Gene fusion    Interstitial deletion    Mouse model    Organoid culture    PTEN    Pb-Cre    Prostate regeneration    TMPRSS2   
期刊:Methods Mol Biol  影响因子:0.0  发表日期: 20180101  PMID: 29786791 


Background: Alternative splicing of the Pkm gene product generates the PKM1 and PKM2 isoforms of ...

关键词: Cancer    PKM2    Soft tissue sarcoma   
期刊:Cancer Metab  影响因子:0.0  发表日期: 20180101  PMID: 29854399 


BACKGROUND: Copy number gain of the D-3-phosphoglycerate dehydrogenase (PHGDH) gene, which encode...

关键词:   
期刊:BMC Cancer  影响因子:2.933  发表日期: 20190722  PMID: 31331318 


Cancers have an altered metabolism, and there is interest in understanding precisely how oncogeni...

期刊:Dis Model Mech  影响因子:4.028  发表日期: 20180807  PMID: 30104199 


关键词:   
期刊:Science  影响因子:41.037  发表日期: 20180601  PMID: 29853672 


Background: While most cancer cells preferentially express the M2 isoform of the glycolytic enzym...

关键词: PDAC    PKM2    Pancreatic cancer    Pyruvate kinase   
期刊:Cancer Metab  影响因子:0.0  发表日期: 20180101  PMID: 30386596 


关键词: Animals    Congenital Abnormalities    Humans    Metabolism, Inborn Errors    Mice    Mutation    NAD    Syndrome   
期刊:N Engl J Med  影响因子:70.67  发表日期: 20170810  PMID: 28792881 


Monoallelic point mutations in the gene encoding the cytosolic, NADP+-dependent enzyme isocitrate...

期刊:J Biol Chem  影响因子:4.106  发表日期: 20181228  PMID: 30381394 


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